Document Details

Document Type : Article In Journal 
Document Title :
Moesin Binds to Bacterial Lipopolysaccharide
ارتباط بروتين المويسين (moesin) بغلاف بكتيريا مادة ليبوبولي ساكارايد (Lipopolysaccharide)
 
Document Language : English 
Abstract : Previous work has demonstrated a role for moesin (member of the ERM family proteins) in lipopolysaccharide mediated events; however, no physical binding to lipopolysaccharide has been reported. Therefore, the aim of this experiment was to study the binding of moesin to lipopolysaccharide. Moesin and radixin recombinant proteins, C- and N- terminus truncated proteins were used. Native gel shift assays were performed using the recombinant proteins and purified E. coli lipopolysaccharide strain O55:B5. The results of the native Gel Shift assay showed that there was direct binding of moesin to lipopolysaccharide. This binding was only evident with the moesin C-terminus recombinant protein. This finding suggests further the important role of moesin in the initial recognition of lipopolysaccharide. 
ISSN : 1319-1004 
Journal Name : Medical Science Journal 
Volume : 16 
Issue Number : 3 
Publishing Year : 1430 AH
2009 AD 
Article Type : Article 
Added Date : Sunday, July 11, 2010 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
خالد هاشم زواويZawawi, Khalid H.Researcher kzawawi@kau.edu.sa

Files

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 27400.pdf pdf 

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