Document Details

Document Type : Article In Journal 
Document Title :
Glucose-6-phosphate Dehydrogenase Activity and Glycogen Content during Chick Neuroretinal Cell Culture
نشاط غنزيم الجلوكوز-6-فوسفات دي هيدروجيناز والمحتوى الجليكوجيني خلال زراعة الخلايا الجينية لطبقة الشبكية العصبية
 
Subject : Zoology 
Document Language : English 
Abstract : Chick embryo neuroretinal (NR) cells transdifferentiate extensively into lens when cultured for several weeks in low glucose (F) medium, but largely inhibited when high levels of supplementary glucose (FG) are present. Glucose-6-phosphate dehydrogenase activity i~ higher in FG (28 mM glucose final) cultures as compared to F (6 mM glucose final) cultures. Another parameter strongly affected by ambient glucose levels is the accumulation of glycogen. Glycogen synthesis increases steadily in FG cultures, but decreases very slightly under F conditions. Glycogen accumulation in FG cultures is largely confined to glial-like (Muller) cells, particularly those underlying clusters of neurons. Thus, high glucose may act in concert with neuronal influences to stimulate or stabilize the normal differentiation of retinal glial cells, whose characteristic features in vivo include glycogen syn!hesis and storage. 
ISSN : 1012-1319 
Journal Name : Science Journal 
Volume : 4 
Issue Number : 1 
Publishing Year : 1412 AH
1992 AD 
Number Of Pages : 10 
Article Type : Article 
Added Date : Sunday, October 11, 2009 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
صالح عبدالعزيز كريمS. A. KARIMResearcher  
ديفيد دي بوميراDaved DE POMERAResearcher  

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